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Treatment-related adverse events were reported by approximately 15% to 22% of subjects in the desloratadine group compared with 14% for the placebo group.

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Although first-generation antihistamines can cause sedation and cognitive impairment, second-generation antihistamines are relatively non-sedating and free of such adverse events owing to their comparative inability to penetrate the blood-brain barrier.

If your child is coughing and also has these symptoms, then he may have or another infection, and may not have pertussis, especially if he has been fully vaccinated and has not been exposed to anyone with pertussis.

Importantly, because antihistamines can theoretically behave as inverse agonists or neutral antagonists, they are more properly described as H1-antihistamines rather than H1-receptor antagonists.

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Just without quotes is reserved for the antivaccine crowd and applied to the small number of deaths from vaccine preventable diseases in unvaccinated children.

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Chronic Idiopathic Urticaria: In multiple-dose, placebo-controlled trials of chronic idiopathic urticaria, 211 patients ages 12 years or older received Desloratadine Tablets and 205 received placebo.

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Only one of the 246 pediatric subjects receiving CLARINEX Syrup in the clinical trials discontinued treatment because of an adverse event.

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8 Immunotherapy will likely play a greater role in the treatment of CDI in the future; immunotherapy with a vaccine and monoclonal antibodies is being studied in clinical trials.

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